A review of parameters and heuristics for guiding metabolic pathfinding
نویسندگان
چکیده
منابع مشابه
A review of parameters and heuristics for guiding metabolic pathfinding
Recent developments in metabolic engineering have led to the successful biosynthesis of valuable products, such as the precursor of the antimalarial compound, artemisinin, and opioid precursor, thebaine. Synthesizing these traditionally plant-derived compounds in genetically modified yeast cells introduces the possibility of significantly reducing the total time and resources required for their...
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چکیده با توسعه شهر نشینی و دخل و تصرف غیر مجاز در حریم رودخانه ها خسارات زیادی به رودخانه و محیط زیست اطراف آن وارده می شود. در حال حاضر بر اساس آئین نامه اصلاح شده بستر و حریم رودخانه ها، حریم کمی رودخانه که بلافاصله پس از بستر قرار می گیرد از 1 تا20 متر از منتهی الیه طرفین بستر رودخانه تعیین، که مقدار دقیق آن در هر بازه از رودخانه مشخص نیست. در کشورهای دیگر روشهای متفاوتی من جمله: درصد ریسک...
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Quadratic assignment problem (QAP) is a well-known problem in the facility location and layout. It belongs to the NP-complete class. There are many heuristic and meta-heuristic methods, which are presented for QAP in the literature. In this paper, we applied 2-opt, greedy 2-opt, 3-opt, greedy 3-opt, and VNZ as heuristic methods and tabu search (TS), simulated annealing, and pa...
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Background: Among non-communicable diseases, cardiovascular diseases (CVDs) account for 44% of all deaths. Among natural alternatives, Nigella sativa (NS) exert beneficial effects on cardio-metabolic factors. This is the first systematic review and meta-analysis protocol aimed to identify all the findings relevant to the effects of NS on cardio-metabolic factors among adults. Methods: This stud...
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Pathfinding is used extensively in modern computer games: more efficient pathfinding allows for more units and bigger games. Several heuristics already exist to improve the performance beyond that of heuristics as the Manhattan distance when used in the A* search algorithm. In this paper, the new Boundary Heuristic (along with several variants) is introduced in order to attempt to increase the ...
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ژورنال
عنوان ژورنال: Journal of Cheminformatics
سال: 2017
ISSN: 1758-2946
DOI: 10.1186/s13321-017-0239-6